Cart
sales@molnova.com
PROTAC-VHL-ligand hydrochloride
CAS No. 1448189-80-7
PROTAC-VHL-ligand hydrochloride( —— )
Catalog No. M11910 CAS No. 1448189-80-7
PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 43 | In Stock |
|
| 100MG | 65 | In Stock |
|
| 500MG | 222 | In Stock |
|
| 1G | 354 | In Stock |
|
Biological Information
-
Product NamePROTAC-VHL-ligand hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionPROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
-
DescriptionPROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayPROTACs
-
TargetE3 Ligase Ligand
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1448189-80-7
-
Formula Weight467.025
-
Molecular FormulaC22H31ClN4O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESCC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)N)O.Cl
-
Chemical NameL-Prolinamide,3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-,(4R)-, hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Bondeson DP, et al. Nat Chem Biol. 2015 Aug;11(8):611-7.
molnova catalog
related products
-
VHL-2
A VHL ligand for PROTAC.
-
Golcadomide
Golcadomide (CC-99282) is a orally active CRBN E3 ligase modulator that induces interactions between CRBN and its neo-substrate, recruiting the target disease-causing proteins and the E3 ubiquitin ligase.
-
Thalidomide-NH-C4-NH...
Thalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
